1696 Linagliptin Tablets 5mg

Linagliptin 5 mg tablets are prescribed for type 2 diabetes management to improve glycemic control when combined with diet and exercise.

What is Linagliptin and How Does It Work?

Linagliptin is an oral antidiabetic medication belonging to the class of DPP-4 (dipeptidyl peptidase-4) inhibitors. It works by blocking the DPP-4 enzyme which breaks down incretin hormones such as GLP-1 and GIP. These incretins help by:

• Increasing insulin release from the pancreas in a glucose-dependent manner

• Decreasing glucagon secretion, reducing glucose production in the liver
  Together, these effects help lower fasting and post-meal blood glucose levels, aiding in better blood sugar control in adults with type 2 diabetes

  4

  .

Indications and Usage

Linagliptin is prescribed as an adjunct to diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It may be used alone or in combination with other antidiabetic agents such as metformin, sulfonylureas, insulin, or SGLT2 inhibitors. It is not suitable for type 1 diabetes or diabetic ketoacidosis

1mg+3

.

Dosage and Administration

The recommended dose of Linagliptin (Tradjenta®) is:

The recommended dosage of TRADJENTA is 5 mg taken orally once daily, with or without food.

Read more on National Institutes of Health (NIH)

This dose should be taken at the same time each day. If a dose is missed, take it as soon as remembered unless it is close to the next scheduled dose. Do not take double doses

National Institutes of Health (NIH)+1

.

Common Side Effects

Common side effects include:

• Nasopharyngitis (cold-like symptoms)

• Cough

• Constipation

• Diarrhea

• Hypoglycemia (especially when combined with other diabetes medicines)

• Headache and mild stomach discomfort may also occur

  4

  .

Serious Side Effects and Warnings

Though rare, serious adverse effects may occur:

• Acute pancreatitis (severe stomach pain spreading to the back with or without vomiting)

• Severe allergic reactions including anaphylaxis and angioedema (swelling of face, lips, tongue, or throat)

• Heart failure symptoms such as swelling, shortness of breath, rapid weight gain

• Severe and disabling joint pain

• Bullous pemphigoid (rare blistering skin condition)
  Patients experiencing these should seek immediate medical attention

  4

  .

Precautions

• Inform your doctor if you have had pancreatitis, gallbladder disease, heart failure, kidney or liver problems, or allergies to linagliptin or related drugs

• Alcohol consumption should be limited as it may increase risk of low blood sugar

• Use caution when combining with insulin or insulin secretagogues to reduce risk of hypoglycemia

• Pregnancy and breastfeeding use should be discussed with a healthcare provider

  3

  .

Storage

Store linagliptin tablets at room temperature between 20°C to 25°C (68°F to 77°F). Keep in a dry place away from moisture, heat, and direct light

WebMD+1

.

Additional Advice

• Always follow your doctor's instructions precisely

• Carry a source of quick sugar if you are at risk of hypoglycemia

• Regular monitoring of blood glucose and periodic health check-ups are essential for safe and effective management

• Do not share medication with others and keep it out of reach of children

  2

  .

Linagliptin Tablets 5 mg are widely prescribed in India and globally to help manage type 2 diabetes effectively by complementing lifestyle changes, with a generally favorable safety profile when used properly.